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The contribution of the acute phase response to the pathogenesis of relapse in chronic-relapsing experimental autoimmune encephalitis models of multiple sclerosis

BACKGROUND: Increased relapse rates in multiple sclerosis (MS) as a consequence of peripheral immune system activation, owing to infection for example, have been widely reported, but the mechanism remains unclear. Acute brain injury models can be exacerbated by augmenting the hepatic acute phase res...

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Detalles Bibliográficos
Autores principales: Mardiguian, Silvy, Ladds, Emma, Turner, Roberta, Shepherd, Hazel, Campbell, Sandra J., Anthony, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622564/
https://www.ncbi.nlm.nih.gov/pubmed/28964257
http://dx.doi.org/10.1186/s12974-017-0969-4