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Polymethoxyflavones: Novel β-Secretase (BACE1) Inhibitors from Citrus Peels

Beta-site amyloid precursor protein (APP) cleaving enzyme1 (BACE1) catalyzes the rate-limiting step of amyloid-β protein (Aβ) generation, and is considered as a prime target for Alzheimer’s disease (AD). In search of a candidate for AD prevention, our efforts exploring the natural BACE1 inhibitor ha...

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Detalles Bibliográficos
Autores principales: Youn, Kumju, Yu, Yoonjin, Lee, Jinhyuk, Jeong, Woo-Sik, Ho, Chi-Tang, Jun, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622733/
https://www.ncbi.nlm.nih.gov/pubmed/28869548
http://dx.doi.org/10.3390/nu9090973