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Polymethoxyflavones: Novel β-Secretase (BACE1) Inhibitors from Citrus Peels
Beta-site amyloid precursor protein (APP) cleaving enzyme1 (BACE1) catalyzes the rate-limiting step of amyloid-β protein (Aβ) generation, and is considered as a prime target for Alzheimer’s disease (AD). In search of a candidate for AD prevention, our efforts exploring the natural BACE1 inhibitor ha...
Autores principales: | Youn, Kumju, Yu, Yoonjin, Lee, Jinhyuk, Jeong, Woo-Sik, Ho, Chi-Tang, Jun, Mira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622733/ https://www.ncbi.nlm.nih.gov/pubmed/28869548 http://dx.doi.org/10.3390/nu9090973 |
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