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Nrf2 Activation by 5-lipoxygenase Metabolites in Human Umbilical Vascular Endothelial Cells

5-hydroxyeicosatetraenoic acid (5-HETE) and 5-hydroxyeicosapentaenoic acid (5-HEPE) are major metabolites produced by 5-lipoxygenase (5-LOX) from arachidonic acid (AA) and eicosapentaenoic acid (EPA). Effects of hydroxides on endothelial cells are unclear, although 5-LOX is known to increase at arte...

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Detalles Bibliográficos
Autores principales: Nagahora, Nozomi, Yamada, Hidetoshi, Kikuchi, Sayaka, Hakozaki, Mayuka, Yano, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622761/
https://www.ncbi.nlm.nih.gov/pubmed/28892009
http://dx.doi.org/10.3390/nu9091001