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Developmental Programming of Obesity and Liver Metabolism by Maternal Perinatal Nutrition Involves the Melanocortin System

Maternal obesity predisposes offspring to metabolic dysfunction and Non-Alcoholic Fatty Liver Disease (NAFLD). Melanocortin-4 receptor (Mc4r)-deficient mouse models exhibit obesity during adulthood. Here, we aim to determine the influence of the Mc4r gene on the liver of mice subjected to perinatal...

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Detalles Bibliográficos
Autores principales: Cordero, Paul, Li, Jiawei, Nguyen, Vi, Pombo, Joaquim, Maicas, Nuria, Novelli, Marco, Taylor, Paul D., Samuelsson, Anne-Maj, Vinciguerra, Manlio, Oben, Jude A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622801/
https://www.ncbi.nlm.nih.gov/pubmed/28930194
http://dx.doi.org/10.3390/nu9091041