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Complement C5-inhibiting therapy for the thrombotic microangiopathies: accumulating evidence, but not a panacea
Thrombotic microangiopathy (TMA), characterized by organ injury occurring consequent to severe endothelial damage, can manifest in a diverse range of diseases. In complement-mediated atypical haemolytic uraemic syndrome (aHUS) a primary defect in complement, such as a mutation or autoantibody leadin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622895/ https://www.ncbi.nlm.nih.gov/pubmed/28980670 http://dx.doi.org/10.1093/ckj/sfx081 |