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In the Wnt of Paneth Cells: Immune-Epithelial Crosstalk in Small Intestinal Crohn’s Disease

Paneth cells, specialized secretory epithelial cells of the small intestine, play a pivotal role in host defense and regulation of microbiota by producing antimicrobial peptides especially—but not only—the human α-defensin 5 (HD5) and HD6. In small intestinal Crohn’s disease (CD) which is an entity...

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Detalles Bibliográficos
Autores principales: Armbruster, Nicole S., Stange, Eduard F., Wehkamp, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622939/
https://www.ncbi.nlm.nih.gov/pubmed/29018451
http://dx.doi.org/10.3389/fimmu.2017.01204