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Ultrafast Comparison of Personal Genomes via Precomputed Genome Fingerprints

We present an ultrafast method for comparing personal genomes. We transform the standard genome representation (lists of variants relative to a reference) into “genome fingerprints” via locality sensitive hashing. The resulting genome fingerprints can be meaningfully compared even when the input dat...

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Detalles Bibliográficos
Autores principales: Glusman, Gustavo, Mauldin, Denise E., Hood, Leroy E., Robinson, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623000/
https://www.ncbi.nlm.nih.gov/pubmed/29018478
http://dx.doi.org/10.3389/fgene.2017.00136