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Plasma and cerebrospinal fluid interleukin-1β during lipopolysaccharide-induced systemic inflammation in ewes implanted or not with slow-release melatonin

BACKGROUND: Interleukin-1β (IL-1β) is important mediator of inflammatory-induced suppression of reproductive axis at the hypothalamic level. At the beginning of inflammation, the main source of cytokines in the cerebrospinal fluid (CSF) is peripheral circulation, while over time, cytokines produced...

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Detalles Bibliográficos
Autores principales: Skipor, Janina, Kowalewska, Marta, Szczepkowska, Aleksandra, Majewska, Anna, Misztal, Tomasz, Jalynski, Marek, Herman, Andrzej P., Zabek, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623061/
https://www.ncbi.nlm.nih.gov/pubmed/29026538
http://dx.doi.org/10.1186/s40104-017-0206-0