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Three-dimensional genome architecture and emerging technologies: looping in disease

Genome compaction is a universal feature of cells and has emerged as a global regulator of gene expression. Compaction is maintained by a multitude of architectural proteins, long non-coding RNAs (lncRNAs), and regulatory DNA. Each component comprises interlinked regulatory circuits that organize th...

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Detalles Bibliográficos
Autores principales: Mishra, Arpit, Hawkins, R. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623062/
https://www.ncbi.nlm.nih.gov/pubmed/28964259
http://dx.doi.org/10.1186/s13073-017-0477-2