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Three-dimensional genome architecture and emerging technologies: looping in disease
Genome compaction is a universal feature of cells and has emerged as a global regulator of gene expression. Compaction is maintained by a multitude of architectural proteins, long non-coding RNAs (lncRNAs), and regulatory DNA. Each component comprises interlinked regulatory circuits that organize th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623062/ https://www.ncbi.nlm.nih.gov/pubmed/28964259 http://dx.doi.org/10.1186/s13073-017-0477-2 |