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Oscillatory stimuli differentiate adapting circuit topologies
Adapting pathways consist of negative feedback loops (NFLs) or incoherent feedforward loops (IFFLs), which we show can be differentiated using oscillatory stimulation: NFLs but not IFFLs generically show ‘refractory period stabilization’ or ‘period skipping’. Using these signatures and genetic rewir...
Autores principales: | Rahi, Sahand Jamal, Larsch, Johannes, Pecani, Kresti, Katsov, Alexander Y., Mansouri, Nahal, Tsaneva-Atanasova, Krasimira, Sontag, Eduardo D., Cross, Frederick R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623142/ https://www.ncbi.nlm.nih.gov/pubmed/28846089 http://dx.doi.org/10.1038/nmeth.4408 |
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