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Repulsive Guidance Molecule a Inhibits Angiogenesis by Downregulating VEGF and Phosphorylated Focal Adhesion Kinase In Vitro

Repulsive guidance molecule a (RGMa) is a major neuron guidance factor in central nervous systems. We previously found that inhibition of RGMa could greatly enhance neural function rehabilitation in rats after MCAO/reperfusion. Neuron guidance factors are often regulators of angiogenesis. However, t...

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Detalles Bibliográficos
Autores principales: Zhang, Gang, Wang, Rong, Cheng, Ke, Li, Qi, Wang, Yu, Zhang, Rongrong, Qin, Xinyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623191/
https://www.ncbi.nlm.nih.gov/pubmed/29018403
http://dx.doi.org/10.3389/fneur.2017.00504