Key differences between 13 KRAS mutation detection technologies and their relevance for clinical practice

INTRODUCTION: This study assessed KRAS mutation detection and functional characteristics across 13 distinct technologies and assays available in clinical practice, in a blinded manner. METHODS: Five distinct KRAS-mutant cell lines were used to study five clinically relevant KRAS mutations: p.G12C, p...

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Detalles Bibliográficos
Autores principales: Sherwood, James L, Brown, Helen, Rettino, Alessandro, Schreieck, Amelie, Clark, Graeme, Claes, Bart, Agrawal, Bhuwnesh, Chaston, Ria, Kong, Benjamin S G, Choppa, Paul, Nygren, Anders O H, Deras, Ina L, Kohlmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623342/
https://www.ncbi.nlm.nih.gov/pubmed/29018576
http://dx.doi.org/10.1136/esmoopen-2017-000235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623342/
https://www.ncbi.nlm.nih.gov/pubmed/29018576
http://dx.doi.org/10.1136/esmoopen-2017-000235

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