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Amino Acid Sensor Kinase Gcn2 Is Required for Conidiation, Secondary Metabolism, and Cell Wall Integrity in the Taxol-Producer Pestalotiopsis microspora

The canonical Gcn2/Cpc1 kinase in fungi coordinates the expression of target genes in response to amino acid starvation. To investigate its possible role in secondary metabolism, we characterized a gcn2 homolog in the taxol-producing fungus Pestalotiopsis microspora. Deletion of the gene led to seve...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Akhberdi, Oren, Hao, Xiaoran, Yu, Xi, Chen, Longfei, Liu, Yanjie, Zhu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623678/
https://www.ncbi.nlm.nih.gov/pubmed/29021785
http://dx.doi.org/10.3389/fmicb.2017.01879