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Amino Acid Sensor Kinase Gcn2 Is Required for Conidiation, Secondary Metabolism, and Cell Wall Integrity in the Taxol-Producer Pestalotiopsis microspora
The canonical Gcn2/Cpc1 kinase in fungi coordinates the expression of target genes in response to amino acid starvation. To investigate its possible role in secondary metabolism, we characterized a gcn2 homolog in the taxol-producing fungus Pestalotiopsis microspora. Deletion of the gene led to seve...
Autores principales: | Wang, Dan, Akhberdi, Oren, Hao, Xiaoran, Yu, Xi, Chen, Longfei, Liu, Yanjie, Zhu, Xudong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623678/ https://www.ncbi.nlm.nih.gov/pubmed/29021785 http://dx.doi.org/10.3389/fmicb.2017.01879 |
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