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Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis

Microtubule-associated protein tau is hyperphosphorylated and aggregated in affected neurons in Alzheimer disease (AD) brains. The tau pathology starts from the entorhinal cortex (EC), spreads to the hippocampus and frontal and temporal cortices, and finally to all isocortex areas, but the cerebellu...

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Detalles Bibliográficos
Autores principales: Hu, Wen, Wu, Feng, Zhang, Yanchong, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623682/
https://www.ncbi.nlm.nih.gov/pubmed/29021756
http://dx.doi.org/10.3389/fnagi.2017.00311