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Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis
Microtubule-associated protein tau is hyperphosphorylated and aggregated in affected neurons in Alzheimer disease (AD) brains. The tau pathology starts from the entorhinal cortex (EC), spreads to the hippocampus and frontal and temporal cortices, and finally to all isocortex areas, but the cerebellu...
Autores principales: | Hu, Wen, Wu, Feng, Zhang, Yanchong, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623682/ https://www.ncbi.nlm.nih.gov/pubmed/29021756 http://dx.doi.org/10.3389/fnagi.2017.00311 |
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