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Snail suppresses cellular senescence and promotes fibroblast‐led cancer cell invasion

Snail, a zinc finger transcription factor, induces an epithelial–mesenchymal transition (EMT) in various cancer and epithelial cells. We investigated the function of Snail (SNAI1) by downregulating its expression with short interfering RNA (siRNA). Suppression of Snail expression induced cellular se...

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Detalles Bibliográficos
Autores principales: Furuya, Satoshi, Endo, Kaori, Takahashi, Akiko, Miyazawa, Keiji, Saitoh, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623692/
https://www.ncbi.nlm.nih.gov/pubmed/28979845
http://dx.doi.org/10.1002/2211-5463.12300