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Rb‐independent E2F3 promotes cell proliferation and alters expression of genes involved in metabolism and inflammation
E2F transcription factors are key targets of the retinoblastoma (Rb) tumor suppressor. Despite extensive studies, the in vivo consequences of disrupting the interaction between Rb and an individual E2F are not clear. Here, we report an E2F mutation that interfered with binding to Rb family proteins...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623693/ https://www.ncbi.nlm.nih.gov/pubmed/28979847 http://dx.doi.org/10.1002/2211-5463.12306 |