Rapid screening of IgG quality attributes – effects on Fc receptor binding

The interactions of therapeutic antibodies with fragment crystallizable γ (Fcγ) receptors and neonatal Fc receptors (FcRn) are measured in vitro as indicators of antibody functional performance. Antibodies are anchored to immune cells through the Fc tail, and these interactions are important for the...

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Detalles Bibliográficos
Autores principales: Geuijen, Karin P. M., Oppers‐Tiemissen, Cindy, Egging, David F., Simons, Peter J., Boon, Louis, Schasfoort, Richard B. M., Eppink, Michel H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623700/
https://www.ncbi.nlm.nih.gov/pubmed/28979843
http://dx.doi.org/10.1002/2211-5463.12283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623700/
https://www.ncbi.nlm.nih.gov/pubmed/28979843
http://dx.doi.org/10.1002/2211-5463.12283

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