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Brucella Rough Mutant Induce Macrophage Death via Activating IRE1α Pathway of Endoplasmic Reticulum Stress by Enhanced T4SS Secretion

Brucella is a Gram-negative facultative intracellular pathogen that causes the worldwide zoonosis, known as brucellosis. Brucella virulence relies mostly on its ability to invade and replicate within phagocytic cells. The type IV secretion system (T4SS) and lipopolysaccharide are two major Brucella...

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Detalles Bibliográficos
Autores principales: Li, Peng, Tian, Mingxing, Bao, Yanqing, Hu, Hai, Liu, Jiameng, Yin, Yi, Ding, Chan, Wang, Shaohui, Yu, Shengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623715/
https://www.ncbi.nlm.nih.gov/pubmed/29021973
http://dx.doi.org/10.3389/fcimb.2017.00422