Cargando…
Brucella Rough Mutant Induce Macrophage Death via Activating IRE1α Pathway of Endoplasmic Reticulum Stress by Enhanced T4SS Secretion
Brucella is a Gram-negative facultative intracellular pathogen that causes the worldwide zoonosis, known as brucellosis. Brucella virulence relies mostly on its ability to invade and replicate within phagocytic cells. The type IV secretion system (T4SS) and lipopolysaccharide are two major Brucella...
Autores principales: | Li, Peng, Tian, Mingxing, Bao, Yanqing, Hu, Hai, Liu, Jiameng, Yin, Yi, Ding, Chan, Wang, Shaohui, Yu, Shengqing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623715/ https://www.ncbi.nlm.nih.gov/pubmed/29021973 http://dx.doi.org/10.3389/fcimb.2017.00422 |
Ejemplares similares
-
Brucella abortus Rough-Type Mutant Induces Ferroptosis and More Oxidative Stress in Infected Macrophages
por: Hu, Hai, et al.
Publicado: (2023) -
Characterization of Brucella abortus mutant strain Δ22915, a potential vaccine candidate
por: Bao, Yanqing, et al.
Publicado: (2017) -
Pyruvate kinase is necessary for Brucella abortus full virulence in BALB/c mouse
por: Gao, Jianpeng, et al.
Publicado: (2016) -
The endoplasmic reticulum stress sensor IRE1α modulates macrophage metabolic function during Brucella abortus infection
por: Guimarães, Erika S., et al.
Publicado: (2023) -
RNAi Screen of Endoplasmic Reticulum–Associated Host Factors Reveals a Role for IRE1α in Supporting Brucella Replication
por: Qin, Qing-Ming, et al.
Publicado: (2008)