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Neuroprotective Mechanisms of Lycium barbarum Polysaccharides Against Ischemic Insults by Regulating NR2B and NR2A Containing NMDA Receptor Signaling Pathways

Glutamate excitotoxicity plays an important role in neuronal death after ischemia. However, all clinical trials using glutamate receptor inhibitors have failed. This may be related to the evidence that activation of different subunit of NMDA receptor will induce different effects. Many studies have...

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Detalles Bibliográficos
Autores principales: Shi, Zhongshan, Zhu, Lihui, Li, Tingting, Tang, Xiaoya, Xiang, Yonghui, Han, Xinjia, Xia, Luoxing, Zeng, Ling, Nie, Junhua, Huang, Yongxia, Tsang, Chi Kwan, Wang, Ying, Lei, Zhigang, Xu, Zaocheng, So, Kwok-fai, Ruan, Yiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623723/
https://www.ncbi.nlm.nih.gov/pubmed/29021742
http://dx.doi.org/10.3389/fncel.2017.00288