Gankyrin induces STAT3 activation in tumor microenvironment and sorafenib resistance in hepatocellular carcinoma

Most hepatocellular carcinomas (HCC) develop as a result of chronic liver inflammation. We have shown that the oncoprotein gankyrin is critical for inflammation‐induced tumorigenesis in the colon. Although the in vitro function of gankyrin is well known, its role in vivo remains to be elucidated. We...

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Detalles Bibliográficos
Autores principales: Sakurai, Toshiharu, Yada, Norihisa, Hagiwara, Satoru, Arizumi, Tadaaki, Minaga, Kosuke, Kamata, Ken, Takenaka, Mamoru, Minami, Yasunori, Watanabe, Tomohiro, Nishida, Naoshi, Kudo, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623735/
https://www.ncbi.nlm.nih.gov/pubmed/28777492
http://dx.doi.org/10.1111/cas.13341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623735/
https://www.ncbi.nlm.nih.gov/pubmed/28777492
http://dx.doi.org/10.1111/cas.13341

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