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Identification of driver copy number alterations in diverse cancer types and application in drug repositioning

Results from numerous studies suggest an important role for somatic copy number alterations (SCNAs) in cancer progression. Our work aimed to identify the drivers (oncogenes or tumor suppressor genes) that reside in recurrently aberrant genomic regions, including a large number of genes or non‐coding...

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Detalles Bibliográficos
Autores principales: Zhou, Wenbin, Zhao, Zhangxiang, Wang, Ruiping, Han, Yue, Wang, Chengyu, Yang, Fan, Han, Ya, Liang, Haihai, Qi, Lishuang, Wang, Chenguang, Guo, Zheng, Gu, Yunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623819/
https://www.ncbi.nlm.nih.gov/pubmed/28719033
http://dx.doi.org/10.1002/1878-0261.12112