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Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging

Viruses assemble large macromolecular repeat structures that become part of the infectious particles or virions. Ribonucleocapsids (RNCs) of negative strand RNA viruses are a prime example where repetition of nucleoprotein (NP) along the genome creates a core polymeric helical scaffold that accommod...

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Detalles Bibliográficos
Autores principales: Darling, Tamarand Lee, Sherwood, Laura Jo, Hayhurst, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623874/
https://www.ncbi.nlm.nih.gov/pubmed/29021793
http://dx.doi.org/10.3389/fimmu.2017.01197