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Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7γ

Nucleophosmin (NPM1) is a multifunctional nucleolar protein implicated in ribogenesis, centrosome duplication, cell cycle control, regulation of DNA repair and apoptotic response to stress stimuli. The majority of these functions are played through the interactions with a variety of protein partners...

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Detalles Bibliográficos
Autores principales: Di Matteo, A, Franceschini, M, Paiardini, A, Grottesi, A, Chiarella, S, Rocchio, S, Di Natale, C, Marasco, D, Vitagliano, L, Travaglini-Allocatelli, C, Federici, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623904/
https://www.ncbi.nlm.nih.gov/pubmed/28920929
http://dx.doi.org/10.1038/oncsis.2017.78