Spatial distribution of disease-associated variants in three-dimensional structures of protein complexes

Next-generation sequencing enables simultaneous analysis of hundreds of human genomes associated with a particular phenotype, for example, a disease. These genomes naturally contain a lot of sequence variation that ranges from single-nucleotide variants (SNVs) to large-scale structural rearrangement...

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Detalles Bibliográficos
Autores principales: Gress, A, Ramensky, V, Kalinina, O V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623905/
https://www.ncbi.nlm.nih.gov/pubmed/28945216
http://dx.doi.org/10.1038/oncsis.2017.79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623905/
https://www.ncbi.nlm.nih.gov/pubmed/28945216
http://dx.doi.org/10.1038/oncsis.2017.79

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