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S100A8/A9 increases the mobilization of pro-inflammatory Ly6C(high) monocytes to the synovium during experimental osteoarthritis
BACKGROUND: Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6C(high) and patrolling Ly6C(low) monocytes. Alarmins S100A8/A9 locally released by the synovium during infl...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623958/ https://www.ncbi.nlm.nih.gov/pubmed/28969686 http://dx.doi.org/10.1186/s13075-017-1426-6 |