S100A8/A9 increases the mobilization of pro-inflammatory Ly6C(high) monocytes to the synovium during experimental osteoarthritis

BACKGROUND: Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6C(high) and patrolling Ly6C(low) monocytes. Alarmins S100A8/A9 locally released by the synovium during infl...

Descripción completa

Detalles Bibliográficos
Autores principales: Cremers, Niels A. J., van den Bosch, Martijn H. J., van Dalen, Stephanie, Di Ceglie, Irene, Ascone, Giuliana, van de Loo, Fons, Koenders, Marije, van der Kraan, Peter, Sloetjes, Annet, Vogl, Thomas, Roth, Johannes, Geven, Edwin J. W., Blom, Arjen B., van Lent, Peter L. E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623958/
https://www.ncbi.nlm.nih.gov/pubmed/28969686
http://dx.doi.org/10.1186/s13075-017-1426-6

Ejemplares similares

Ejemplares similares