DEC2 Blocks the Effect of the ARNTL2/NPAS2 Dimer on the Expression of PER3 and DBP

The expression of clock genes ARNTL2, NPAS2 and DEC2 are disturbed in rheumatoid arthritis, an autoimmune disease with circadian variation of symptoms. We have shown that TNF is a potent inducer of these genes. We investigated the regulation of ARNTL2 and NPAS2 by TNF and elucidated their effect on...

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Detalles Bibliográficos
Autores principales: Olkkonen, Juri, Kouri, Vesa-Petteri, Kuusela, Elina, Ainola, Mari, Nordström, Dan, Eklund, Kari K., Mandelin, Jami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624067/
https://www.ncbi.nlm.nih.gov/pubmed/30210560
http://dx.doi.org/10.5334/jcr.149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624067/
https://www.ncbi.nlm.nih.gov/pubmed/30210560
http://dx.doi.org/10.5334/jcr.149

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