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Citalopram Ameliorates Impairments in Spatial Memory and Synaptic Plasticity in Female 3xTgAD Mice

Alzheimer's disease (AD) is the primary cause of dementia. There is no effective treatment. Amyloid-β peptide (Aβ) plays an important role in the pathogenesis and thus strategies suppressing Aβ production and accumulation seem promising. Citalopram is an antidepressant drug and can decrease Aβ...

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Detalles Bibliográficos
Autores principales: Wei, Zhang, Junhong, Guo, Xiaoyuan, Niu, Jie, Wang, Zhaojun, Wang, Meina, Wu, Wei, Yang, Jun, Zhang, Jinshun, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624171/
https://www.ncbi.nlm.nih.gov/pubmed/29075638
http://dx.doi.org/10.1155/2017/1238687