5-Aminoimidazole-4-carboxamide ribonucleoside-induced autophagy flux during differentiation of monocytic leukemia cells

Pharmacological modulators of AMP-dependent kinase (AMPK) have been suggested in treatment of cancer. The biguanide metformin and 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) have been reported to inhibit proliferation of solid tumors and hematological malignancies, but their role in differ...

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Detalles Bibliográficos
Autores principales: Dembitz, Vilma, Lalic, Hrvoje, Visnjic, Dora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624282/
https://www.ncbi.nlm.nih.gov/pubmed/28975042
http://dx.doi.org/10.1038/cddiscovery.2017.66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624282/
https://www.ncbi.nlm.nih.gov/pubmed/28975042
http://dx.doi.org/10.1038/cddiscovery.2017.66

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