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5-Aminoimidazole-4-carboxamide ribonucleoside-induced autophagy flux during differentiation of monocytic leukemia cells

Pharmacological modulators of AMP-dependent kinase (AMPK) have been suggested in treatment of cancer. The biguanide metformin and 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) have been reported to inhibit proliferation of solid tumors and hematological malignancies, but their role in differ...

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Detalles Bibliográficos
Autores principales:	Dembitz, Vilma, Lalic, Hrvoje, Visnjic, Dora
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624282/ https://www.ncbi.nlm.nih.gov/pubmed/28975042 http://dx.doi.org/10.1038/cddiscovery.2017.66

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