Regulation of DNA Repair pathway choice in S/G2 by the NHEJ inhibitor CYREN

Classical non-homologous end joining 1 (cNHEJ) and homologous recombination 2 (HR) compete for the repair of double stranded breaks of DNA during the cell cycle. HR is inhibited in G1 phase of the cell cycle, but both pathways are active in S and G2 phases. Why cNHEJ does not always outcompete HR in...

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Detalles Bibliográficos
Autores principales: Arnoult, Nausica, Correia, Adriana, Ma, Jiao, Merlo, Anna, Garcia-Gomez, Sara, Maric, Marija, Tognetti, Marco, Benner, Christopher W., Boulton, Simon J., Saghatelian, Alan, Karlseder, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624508/
https://www.ncbi.nlm.nih.gov/pubmed/28959974
http://dx.doi.org/10.1038/nature24023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624508/
https://www.ncbi.nlm.nih.gov/pubmed/28959974
http://dx.doi.org/10.1038/nature24023

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