Cargando…

Mitochondrial permeabilisation engages NF-κB dependent anti-tumour activity under caspase deficiency

Apoptosis represents a key anti-cancer therapeutic effector mechanism. During apoptosis, mitochondrial outer membrane permeabilisation (MOMP) typically kills cells even in the absence of caspase activity. Caspase activity can also have a variety of unwanted consequences that include DNA-damage. We t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giampazolias, Evangelos, Zunino, Barbara, Dhayade, Sandeep, Bock, Florian, Cloix, Catherine, Cao, Kai, Roca, Alba, Lopez, Jonathan, Ichim, Gabriel, Proïcs, Emma, Rubio-Patiño, Camila, Fort, Loic, Yatim, Nader, Woodham, Emma, Orozco, Susana, Taraborrelli, Lucia, Peltzer, Nieves, Lecis, Daniele, Machesky, Laura, Walczak, Henning, Albert, Matthew L., Milling, Simon, Oberst, Andrew, Ricci, Jean-Ehrland, Ryan, Kevin M., Blyth, Karen, Tait, Stephen W.G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624512/ https://www.ncbi.nlm.nih.gov/pubmed/28846096 http://dx.doi.org/10.1038/ncb3596

Ejemplares similares

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis
por: Riley, Joel S, et al.
Publicado: (2018)

Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics
por: Rubio-Patiño, Camila, et al.
Publicado: (2016)

Exploring the ultrashort pulse laser parameter space for membrane permeabilisation in mammalian cells
por: Rudhall, Andrew P., et al.
Publicado: (2012)

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation
por: Martín-Sánchez, F, et al.
Publicado: (2016)

Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin
por: Woodham, Emma F., et al.
Publicado: (2017)

Necroptosis: Fifty shades of RIPKs
por: Ichim, Gabriel, et al.
Publicado: (2014)

Mito-priming as a method to engineer Bcl-2 addiction
por: Lopez, Jonathan, et al.
Publicado: (2016)

Calpain and Reactive Oxygen Species Targets Bax for Mitochondrial Permeabilisation and Caspase Activation in Zerumbone Induced Apoptosis
por: Sobhan, Praveen K., et al.
Publicado: (2013)

Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients using two cell types
por: Tomas, Cara, et al.
Publicado: (2019)

Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function
por: Campbell, Kirsteen J., et al.
Publicado: (2021)

Correction: Calpain and Reactive Oxygen Species Targets Bax for Mitochondrial Permeabilisation and Caspase Activation in Zerumbone Induced Apoptosis
por: Sobhan, Praveen K., et al.
Publicado: (2022)

Transient nuclear lamin A/C accretion aids in recovery from vapor nanobubble-induced permeabilisation of the plasma membrane
por: Houthaeve, Gaëlle, et al.
Publicado: (2022)

Generation of myocyte agonal Ca(2+) waves and contraction bands in perfused rat hearts following irreversible membrane permeabilisation
por: Morishita, Yuma, et al.
Publicado: (2023)

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death
por: Ichim, Gabriel, et al.
Publicado: (2015)

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death
por: Ichim, Gabriel, et al.
Publicado: (2015)

The antibiotic peptaibol alamethicin from Trichoderma permeabilises Arabidopsis root apical meristem and epidermis but is antagonised by cellulase-induced resistance to alamethicin
por: Dotson, Bradley R., et al.
Publicado: (2018)

Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P(2) to mediate tumour cell permeabilisation
por: Phan, Thanh Kha, et al.
Publicado: (2015)

Eukaryotic Cell Permeabilisation to Identify New Putative Chlamydial Type III Secretion System Effectors Secreted within Host Cell Cytoplasm
por: Kebbi-Beghdadi, Carole, et al.
Publicado: (2020)

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour
por: Tyrrell, Benjamin J., et al.
Publicado: (2016)

Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
por: Cao, Kai, et al.
Publicado: (2022)

Impact of Formate Supplementation on Body Weight and Plasma Amino Acids
por: Dhayade, Sandeep, et al.
Publicado: (2020)

Linear ubiquitination in immunity
por: Shimizu, Yutaka, et al.
Publicado: (2015)

Ubiquitin in the immune system
por: Zinngrebe, Julia, et al.
Publicado: (2014)

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity
por: Haller, Martina, et al.
Publicado: (2015)

MCL-1 is a prognostic indicator and drug target in breast cancer
por: Campbell, Kirsteen J., et al.
Publicado: (2018)

LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation
por: Zinngrebe, Julia, et al.
Publicado: (2016)

The MSP‐RON axis stimulates cancer cell growth in models of triple negative breast cancer
por: Millar, Rhona, et al.
Publicado: (2020)

The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis
por: Shimizu, Yutaka, et al.
Publicado: (2017)

Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death
por: Bock, Florian J., et al.
Publicado: (2021)

LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
por: Taraborrelli, Lucia, et al.
Publicado: (2018)

Cell Death-Related Ubiquitin Modifications in Inflammatory Syndromes: From Mice to Men
por: Peltzer, Nieves, et al.
Publicado: (2022)

Killing cells using light (activated) sabers
por: Tait, Stephen W.G.
Publicado: (2022)

Fascin Is Regulated by Slug, Promotes Progression of Pancreatic Cancer in Mice, and Is Associated With Patient Outcomes
por: Li, Ang, et al.
Publicado: (2014)

Phenotypic analysis of Myo10 knockout (Myo10(tm2/tm2)) mice lacking full-length (motorized) but not brain-specific headless myosin X
por: Bachg, Anne C., et al.
Publicado: (2019)

Monocytes mediate Salmonella Typhimurium‐induced tumor growth inhibition in a mouse melanoma model
por: Johnson, Síle A., et al.
Publicado: (2021)

Mitochondrial DNA in inflammation and immunity
por: Riley, Joel S, et al.
Publicado: (2020)

CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors
por: Whitelaw, Jamie A., et al.
Publicado: (2019)

Cell death and inflammation during obesity: “Know my methods, WAT(son)”
por: Hildebrandt, Ximena, et al.
Publicado: (2022)

Epilepsy, Regulation of Brain Energy Metabolism and Neurotransmission
por: Cloix, Jean-François, et al.
Publicado: (2009)

Targeting immunogenic cell death in cancer
por: Ahmed, Asma, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_q07ddsjgho2q4f7opv71cqu0tg