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Stem Cell Differentiation as a Non-Markov Stochastic Process

Pluripotent stem cells can self-renew in culture and differentiate along all somatic lineages in vivo. While much is known about the molecular basis of pluripotency, the mechanisms of differentiation remain unclear. Here, we profile individual mouse embryonic stem cells as they progress along the ne...

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Detalles Bibliográficos
Autores principales: Stumpf, Patrick S., Smith, Rosanna C.G., Lenz, Michael, Schuppert, Andreas, Müller, Franz-Josef, Babtie, Ann, Chan, Thalia E., Stumpf, Michael P.H., Please, Colin P., Howison, Sam D., Arai, Fumio, MacArthur, Ben D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624514/
https://www.ncbi.nlm.nih.gov/pubmed/28957659
http://dx.doi.org/10.1016/j.cels.2017.08.009