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Stem Cell Differentiation as a Non-Markov Stochastic Process
Pluripotent stem cells can self-renew in culture and differentiate along all somatic lineages in vivo. While much is known about the molecular basis of pluripotency, the mechanisms of differentiation remain unclear. Here, we profile individual mouse embryonic stem cells as they progress along the ne...
Autores principales: | Stumpf, Patrick S., Smith, Rosanna C.G., Lenz, Michael, Schuppert, Andreas, Müller, Franz-Josef, Babtie, Ann, Chan, Thalia E., Stumpf, Michael P.H., Please, Colin P., Howison, Sam D., Arai, Fumio, MacArthur, Ben D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624514/ https://www.ncbi.nlm.nih.gov/pubmed/28957659 http://dx.doi.org/10.1016/j.cels.2017.08.009 |
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