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Induced Pluripotent Stem Cells derived Muscle Progenitors Effectively Mitigate Muscular Dystrophy through Restoring the Dystrophin Distribution

BACKGROUND: Duchenne Muscular Dystrophy (DMD) is a recessive form of muscular disorder, resulting from the dystrophin gene mutations in X-chromosome. Application of embryonic stem cells or adult stem cells has demonstrated the therapeutic effects on DMD through both cell-based and non-cell based mec...

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Detalles Bibliográficos
Autores principales: Cai, Wen-Feng, Huang, Wei, Wang, Lei, Wang, Jia-Peng, Zhang, Lu, Ashraf, Muhammad, Wu, Shizheng, Wang, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624556/
https://www.ncbi.nlm.nih.gov/pubmed/28979820
http://dx.doi.org/10.4172/2157-7633.1000361