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Breast cancer cell-derived fibroblast growth factors enhance osteoclast activity and contribute to the formation of metastatic lesions

Fibroblast growth factors (FGFs) and their receptors (FGFRs) have been implicated in promoting breast cancer growth and progression. While the autocrine effects of FGFR activation in tumor cells have been extensively studied, little is known about the effects of tumor cell-derived FGFs on cells in t...

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Detalles Bibliográficos
Autores principales: Aukes, Kelly, Forsman, Cynthia, Brady, Nicholas J., Astleford, Kristina, Blixt, Nicholas, Sachdev, Deepali, Jensen, Eric D., Mansky, Kim C., Schwertfeger, Kathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624603/
https://www.ncbi.nlm.nih.gov/pubmed/28968431
http://dx.doi.org/10.1371/journal.pone.0185736