Changes in the cellular microRNA profile by the intracellular expression of HIV-1 Tat regulator: A potential mechanism for resistance to apoptosis and impaired proliferation in HIV-1 infected CD4+ T cells

HIV-1 induces changes in the miRNA expression profile of infected CD4+ T cells that could improve viral replication. HIV-1 regulator Tat modifies the cellular gene expression and has been appointed as an RNA silencing suppressor. Tat is a 101-residue protein codified by two exons that regulates the...

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Detalles Bibliográficos
Autores principales: Sánchez-Del Cojo, María, López-Huertas, María Rosa, Díez-Fuertes, Francisco, Rodríguez-Mora, Sara, Bermejo, Mercedes, López-Campos, Guillermo, Mateos, Elena, Jiménez-Tormo, Laura, Gómez-Esquer, Francisco, Díaz-Gil, Gema, Alcamí, José, Coiras, Mayte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624617/
https://www.ncbi.nlm.nih.gov/pubmed/28968466
http://dx.doi.org/10.1371/journal.pone.0185677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624617/
https://www.ncbi.nlm.nih.gov/pubmed/28968466
http://dx.doi.org/10.1371/journal.pone.0185677

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