Cargando…

Changes in the cellular microRNA profile by the intracellular expression of HIV-1 Tat regulator: A potential mechanism for resistance to apoptosis and impaired proliferation in HIV-1 infected CD4+ T cells

HIV-1 induces changes in the miRNA expression profile of infected CD4+ T cells that could improve viral replication. HIV-1 regulator Tat modifies the cellular gene expression and has been appointed as an RNA silencing suppressor. Tat is a 101-residue protein codified by two exons that regulates the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sánchez-Del Cojo, María, López-Huertas, María Rosa, Díez-Fuertes, Francisco, Rodríguez-Mora, Sara, Bermejo, Mercedes, López-Campos, Guillermo, Mateos, Elena, Jiménez-Tormo, Laura, Gómez-Esquer, Francisco, Díaz-Gil, Gema, Alcamí, José, Coiras, Mayte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624617/ https://www.ncbi.nlm.nih.gov/pubmed/28968466 http://dx.doi.org/10.1371/journal.pone.0185677

Ejemplares similares

Intracellular expression of Tat alters mitochondrial functions in T cells: a potential mechanism to understand mitochondrial damage during HIV-1 replication
por: Rodríguez-Mora, Sara, et al.
Publicado: (2015)

PKCθ and HIV-1 Transcriptional Regulator Tat Co-exist at the LTR Promoter in CD4(+) T Cells
por: López-Huertas, María Rosa, et al.
Publicado: (2016)

Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon
por: López-Huertas, M. R., et al.
Publicado: (2010)

Transcriptomic Evidence of the Immune Response Activation in Individuals With Limb Girdle Muscular Dystrophy Dominant 2 (LGMDD2) Contributes to Resistance to HIV-1 Infection
por: Diez-Fuertes, Francisco, et al.
Publicado: (2022)

Modifications in host cell structure and functions mediated by Tat intracellular expression are greatly dependent on the second exon
por: López-Huertas, María Rosa, et al.
Publicado: (2009)

Molecular mechanisms involved in HIV latency and implications for HIV treatment and eradication
por: Alcami, Jose, et al.
Publicado: (2010)

Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IκBα and enhances HIV-1 replication in human T lymphocytes
por: Coiras, Mayte, et al.
Publicado: (2008)

IL-7 Induces SAMHD1 Phosphorylation in CD4+ T Lymphocytes, Improving Early Steps of HIV-1 Life Cycle
por: Coiras, Mayte, et al.
Publicado: (2016)

The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1
por: López-Huertas, María Rosa, et al.
Publicado: (2017)

Basal shuttle of NF-κB/IκBα in resting T lymphocytes regulates HIV-1 LTR dependent expression
por: Coiras, Mayte, et al.
Publicado: (2007)

The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection
por: Rodríguez-Mora, Sara, et al.
Publicado: (2019)

Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication
por: Coiras, Mayte, et al.
Publicado: (2013)

Dynamics of HIV Reservoir and HIV-1 Viral Splicing in HCV-Exposed Individuals after Elimination with DAAs or Spontaneous Clearance
por: Martínez-Román, Paula, et al.
Publicado: (2022)

Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways
por: Olmedo, Dionisio A., et al.
Publicado: (2017)

Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein
por: Charnay, Nicolas, et al.
Publicado: (2009)

Omic Technologies in HIV: Searching Transcriptional Signatures Involved in Long-Term Non-Progressor and HIV Controller Phenotypes
por: De La Torre-Tarazona, Erick, et al.
Publicado: (2022)

Impact of Transcriptome and Gut Microbiome on the Response of HIV-1 Infected Individuals to a Dendritic Cell-Based HIV Therapeutic Vaccine
por: Pastor-Ibáñez, Roque, et al.
Publicado: (2021)

Hepatitis C Virus Influences HIV-1 Viral Splicing in Coinfected Patients
por: Martínez-Román, Paula, et al.
Publicado: (2020)

HCV-coinfection is related to an increased HIV-1 reservoir size in cART-treated HIV patients: a cross-sectional study
por: López-Huertas, Maria Rosa, et al.
Publicado: (2019)

HIV-1 Tat and T cell apoptosis
por: Krammer, Peter H
Publicado: (2006)

HIV-1 Tat alters neuronal intrinsic excitability
por: Francesconi, Walter, et al.
Publicado: (2018)

Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription
por: Ammosova, Tatyana, et al.
Publicado: (2006)

The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disorders
por: Mediouni, Sonia, et al.
Publicado: (2015)

Persistent Overactive Cytotoxic Immune Response in a Spanish Cohort of Individuals With Long-COVID: Identification of Diagnostic Biomarkers
por: Galán, Miguel, et al.
Publicado: (2022)

Impaired Cytotoxic Response in PBMCs From Patients With COVID-19 Admitted to the ICU: Biomarkers to Predict Disease Severity
por: Vigón, Lorena, et al.
Publicado: (2021)

Proteomic characterization of HIV-1 Tat interactome
por: Gautier, VW, et al.
Publicado: (2006)

HIV-1 Tat: Role in Bystander Toxicity
por: Ajasin, David, et al.
Publicado: (2020)

Identification of Immunological Parameters as Predictive Biomarkers of Relapse in Patients with Chronic Myeloid Leukemia on Treatment-Free Remission
por: Vigón, Lorena, et al.
Publicado: (2020)

HIV-1 Tat interacts with LIS1 protein
por: Epie, Nicolas, et al.
Publicado: (2005)

Insight in miRNome of Long-Term Non-Progressors and Elite Controllers Exposes Potential RNAi Role in Restraining HIV-1 Infection
por: Ayala-Suárez, Rubén, et al.
Publicado: (2020)

HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription
por: Ivanov, Andrey, et al.
Publicado: (2018)

Identification of HIV-1 Tat-Associated Proteins Contributing to HIV-1 Transcription and Latency
por: Jean, Maxime Junior, et al.
Publicado: (2017)

HIV-1 and HIV-1-Tat Induce Mitochondrial DNA Damage in Human Neurons
por: Darbinian, Nune, et al.
Publicado: (2020)

HEXIM1-Tat chimera inhibits HIV-1 replication
por: Leoz, Marie, et al.
Publicado: (2018)

HIV-1 Tat interaction with Dicer: requirement for RNA
por: Bennasser, Yamina, et al.
Publicado: (2006)

Recruitment and Activation of RSK2 by HIV-1 Tat
por: Hetzer, Claudia, et al.
Publicado: (2007)

HIV-1 Tat protein enhances Microtubule polymerization
por: de Mareuil, Jean, et al.
Publicado: (2005)

Impact of Tat Genetic Variation on HIV-1 Disease
por: Li, Luna, et al.
Publicado: (2012)

In vitro nuclear interactome of the HIV-1 Tat protein
por: Gautier, Virginie W, et al.
Publicado: (2009)

Structure-function relationships of the HIV-1 Tat protein
por: Loret, Erwann P
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_dc079ni50es7lq47qgfhmgpj3t