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The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory ‘M1’ human macrophages

The translocator protein (TSPO) is a mitochondrial membrane protein, of as yet uncertain function. Its purported high expression on activated macrophages, has lent utility to TSPO targeted molecular imaging in the form of positron emission tomography (PET), as a means to detect and quantify inflamma...

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Detalles Bibliográficos
Autores principales: Narayan, Nehal, Mandhair, Harpreet, Smyth, Erica, Dakin, Stephanie Georgina, Kiriakidis, Serafim, Wells, Lisa, Owen, David, Sabokbar, Afsie, Taylor, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624624/
https://www.ncbi.nlm.nih.gov/pubmed/28968465
http://dx.doi.org/10.1371/journal.pone.0185767