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R1R2 peptide ameliorates pulmonary fibrosis in mice through fibrocyte migration and differentiation
Circulating fibrocytes play a key role in the pathogenesis of pulmonary fibrosis. Fibrocytes are bone marrow-derived leukocytes, which enter the lungs in response to their chemoattractant CXCL12 and differentiate into fibroblasts or myofibroblasts, leading to excess deposition of the collagen-rich e...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624629/ https://www.ncbi.nlm.nih.gov/pubmed/28968441 http://dx.doi.org/10.1371/journal.pone.0185811 |