T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy

HIV-specific CD8(+) T-cell responses limit viral replication in untreated infection. After the initiation of antiretroviral therapy (ART), these responses decay and the infected cell population that remains is commonly considered to be invisible to T-cells. We hypothesized that HIV antigen recogniti...

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Detalles Bibliográficos
Autores principales: Thomas, Allison S., Jones, Kimberley L., Gandhi, Rajesh T., McMahon, Deborah K., Cyktor, Joshua C., Chan, Dora, Huang, Szu-Han, Truong, Ronald, Bosque, Alberto, Macedo, Amanda B., Kovacs, Colin, Benko, Erika, Eron, Joseph J., Bosch, Ronald J., Lalama, Christina M., Simmens, Samuel, Walker, Bruce D., Mellors, John W., Jones, R. Brad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624641/
https://www.ncbi.nlm.nih.gov/pubmed/28931091
http://dx.doi.org/10.1371/journal.ppat.1006629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624641/
https://www.ncbi.nlm.nih.gov/pubmed/28931091
http://dx.doi.org/10.1371/journal.ppat.1006629

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