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FCGRs Polymorphisms and Response to Trastuzumab in Patients With HER2-Positive Breast Cancer: Far From Predictive Value?

BACKGROUND: The aim of the study was to validate the association between the Arg166His polymorphisms of the Fc immunoglobulin receptor 2A (FCGR2A) and the Val212Phe of FCGR3A and pathological clinical response (pCR) to trastuzumab in HER2-positive breast cancer patients. METHODS: Polymorphisms were...

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Detalles Bibliográficos
Autores principales: Botticelli, Andrea, Mazzuca, Federica, Borro, Marina, Mazzotti, Eva, La Torre, Marco, Bonifacino, Adriana, Ciabatta, Francesca Romana, Gentile, Giovanna, Maddalena, Chiara, Simmaco, Maurizio, Marchetti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624668/
https://www.ncbi.nlm.nih.gov/pubmed/28983344
http://dx.doi.org/10.14740/wjon934w