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Generation and Characterization of a Novel Mouse Line, Keratocan-rtTA (Kera(RT)), for Corneal Stroma and Tendon Research
PURPOSE: We created a novel inducible mouse line Keratocan-rtTA (Kera(RT)) that allows specific genetic modification in corneal keratocytes and tenocytes during development and in adults. METHODS: A gene-targeting vector (Kera- IRES2-rtTA3) was constructed and inserted right after the termination co...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624774/ https://www.ncbi.nlm.nih.gov/pubmed/28973326 http://dx.doi.org/10.1167/iovs.17-22661 |