The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase

PURPOSE: While nitric oxide (NO) donors are emerging as treatments for glaucoma, the mechanism by which NO lowers intraocular pressure (IOP) is unclear. NO activates the enzyme guanylyl cyclase (GC) to produce cyclic guanosine monophosphate. We studied the ocular effects of inhaled and topically app...

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Detalles Bibliográficos
Autores principales: Muenster, Stefan, Lieb, Wolfgang S., Fabry, Gregor, Allen, Kaitlin N., Kamat, Shivani S., Guy, Ann H., Dordea, Ana C., Teixeira, Leandro, Tainsh, Robert E., Yu, Binglan, Zhu, Wei, Ashpole, Nicole E., Malhotra, Rajeev, Brouckaert, Peter, Bloch, Donald B., Scherrer-Crosbie, Marielle, Stamer, W. Daniel, Kuehn, Markus H., Pasquale, Louis R., Buys, Emmanuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624778/
https://www.ncbi.nlm.nih.gov/pubmed/28973329
http://dx.doi.org/10.1167/iovs.17-22168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624778/
https://www.ncbi.nlm.nih.gov/pubmed/28973329
http://dx.doi.org/10.1167/iovs.17-22168

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