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The Syk Tyrosine Kinase Is Required for Skin Inflammation in an In Vivo Mouse Model of Epidermolysis Bullosa Acquisita

The inflammatory form of epidermolysis bullosa acquisita is caused by autoantibodies against type VII collagen (C7), a component of the dermal-epidermal junction. We have previously shown that myeloid Src family kinases mediate skin inflammation triggered by anti-C7 antibodies. Here we identify the...

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Detalles Bibliográficos
Autores principales: Németh, Tamás, Virtic, Oana, Sitaru, Cassian, Mócsai, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624865/
https://www.ncbi.nlm.nih.gov/pubmed/28576735
http://dx.doi.org/10.1016/j.jid.2017.05.017